ICD Guidelines for Neoplasm – CPC Exam Preparation

Understanding the ICD guidelines for neoplasms is essential for accurate medical coding, especially for those preparing for the Certified Professional Coder (CPC) exam.

Neoplasms, whether benign or malignant, require specific coding considerations to ensure proper documentation and reimbursement. Here is a concise guide to the key points relevant to neoplasm coding and sequencing.

To assign codes from neoplasms, we need to identify the site of neoplasm and type of neoplasm.

we look into what are neoplasm and types.

Neoplasm – A neoplasm is an abnormal and uncontrolled growth of tissue, commonly referred to as a tumor.

Types of Neoplasms: Neoplasms can be categorized into various types based on their characteristics, origin, and behavior. Some common types include:

Benign Neoplasm:

  • Non-cancerous growth.
  • Typically localized and does not invade surrounding tissues.
  • Generally slow-growing and does not spread to other parts of the body.

Malignant Neoplasm (Cancer):

  • Cancerous growth with the potential to invade nearby tissues and spread to distant organs.

Primary Malignant Neoplasm: A primary malignant neoplasm is an initial cancerous growth that originates in a particular tissue or organ. It is the site where the cancerous cells first developed.

Secondary Malignant Neoplasm (Metastasis): A secondary malignant neoplasm, also known as metastasis, occurs when cancer cells from the primary site travel to other parts of the body and establish new tumors.

In-Situ Neoplasm:

  • Refers to abnormal cell growth that is confined to the original site.
  • Has not invaded neighboring tissues or spread to other parts of the body.

Uncertain Histologic Behavior Neoplasm:

  • Neoplasm with characteristics that make it difficult to predict its biological behavior.
  • Further testing or observation may be required to determine whether it is benign or malignant.

Ectopic Tissue Neoplasm:

  • Neoplasm originating from tissue that is not in its usual location.
  • Example: Ectopic pancreatic malignant neoplasm involving the stomach.

Disseminated Malignant Neoplasm:

  • Advanced metastatic disease where cancer cells have spread widely, often with no known primary or secondary sites specified.

Neoplasms, whether benign or malignant, require specific coding considerations to ensure proper documentation and reimbursement. Here is a concise guide to the key points relevant to neoplasm coding and sequencing.

Determining Neoplasm Type:

  • Differentiate between benign, in-situ, malignant, or neoplasms or uncertain histologic behavior.
  • Identify any secondary (metastatic) sites if the neoplasm is malignant.

ICD guidelines for neoplasm

Treatment Direction

  • Principal diagnosis is the malignancy, when the patient came in for the treatment of malignancy.
  • Exception: If admission is solely for chemotherapy, immunotherapy, or radiation therapy, use appropriate Z51.– code.


When a patient is admitted due to a primary neoplasm with metastasis and the focus of treatment is on the secondary site, designate the secondary neoplasm as the principal diagnosis.

This holds true even if the primary malignancy is still present.

Sequencing of complications

Complications associated with malignancies or their treatment can encompass a range of health issues that arise as a result of the cancer itself or the therapies administered.

Here is an elaboration of how to code these complications associated with malignancy and its treatment.

Anemia Associated with Malignancy:

  • Occurs when the body has a lower-than-normal red blood cell count due to the malignancy.
  • Coding: If the admission is for anemia management associated with malignancy, the principal diagnosis is the malignancy, followed by the appropriate anemia code.

Anemia Associated with Chemotherapy, Immunotherapy, and Radiation Therapy

Anemia arises due to the adverse effects of chemotherapy, immunotherapy, or radiation therapy on the bone marrow.

Coding: For management of anemia associated with these treatments, the anemia code is sequenced first, followed by the appropriate codes for the neoplasm and the adverse effect.

T45.1X5-, Adverse effect of antineoplastic and immunosuppressive drugs

Management of Dehydration Due to Malignancy

Dehydration may result from the malignancy itself, affecting the body’s fluid balance.

Coding: If the admission is for managing dehydration due to malignancy, the dehydration code is sequenced first, followed by the code(s) for the malignancy.

Complications from Surgical Procedures

Surgical interventions for neoplasms can lead to various complications, such as infections, bleeding, or organ dysfunction.

Coding: If the encounter is for treating a complication resulting from a surgical procedure performed for the neoplasm, designate the complication as the principal or first-listed diagnosis if treatment is directed at resolving the complication.

Primary Malignancy Previously Excised

Use category Z85 for personal history of malignant neoplasm when a primary malignancy has been excised.

If evidence of extension, invasion, or metastasis exists, code secondary malignant neoplasm as principal diagnosis and Z85 code for personal history of primary malignancy.

Admissions Involving Chemotherapy, Immunotherapy, and Radiation Therapy

If a patient admission/encounter is solely for the administration of chemotherapy, immunotherapy or external beam radiation therapy assign code

Z51.0, Encounter for antineoplastic radiation therapy, or

Z51.11, Encounter for antineoplastic chemotherapy, or

Z51.12, Encounter for antineoplastic immunotherapy as the first-listed or principal diagnosis.

The malignancy for which the therapy is being administered should be assigned as a secondary diagnosis.

If complications developed after admission

When a patient is admitted for the purpose of external beam radiotherapy, immunotherapy or chemotherapy and develops complications such as uncontrolled nausea and vomiting or dehydration, the principal or first-listed diagnosis is the therapy codes, followed by any codes for the complications.

Coding for Pain Control/Management

Code G89.3 is applied for pain explicitly attributed to cancer, whether arising from primary or secondary malignancies or tumors.

This code is appropriate for both acute and chronic pain and can be designated as the principal or first-listed code when the admission or encounter is primarily for pain control or pain management.

In such cases, the neoplasm causing the pain should be reported as an additional diagnosis.

Conclusion

For CPC aspirants, mastering neoplasm coding is pivotal.

Understanding primary and secondary malignancies, treatment complications, and accurate sequencing is crucial.

To reinforce your skills, take advantage of a complimentary ICD guidelines for neoplasm coding practice test.

This hands-on experience will enhance your readiness for the CPC exam, ensuring you’re adept at accurately coding and sequencing neoplastic conditions.

Access the free practice test here and boost your confidence for success in the challenging field of medical coding.

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